Adverse Drug Reaction Trainer

A 3-year-old boy with lethargy, vomiting and elevated INR

A 32-year-old woman with a rash and mucosal erosions

A 65-year-old man with a falling platelet count and a leg DVT on day 7 of surgery

Achilles tendon rupture in a man on ciprofloxacin and prednisolone

Acute anaphylaxis after a new antibiotic infusion

Acute dystonia in a 22-year-old man after haloperidol

Acute gout after initiation of bendroflumethiazide

Acute kidney injury in a 78-year-old woman with recent gastroenteritis and new NSAID use

Acute kidney injury in a diabetic man after contrast CT

Acute wheeze after aspirin in a woman with asthma and nasal polyps

Agitation, sweating and hyperreflexia after adding tramadol to sertraline

Ataxia, nystagmus and gum overgrowth after phenytoin dose increase

Confusion and Severe Hyponatraemia in an 82-Year-Old Woman on Multiple Medications

Dry cough and breathlessness in a woman on methotrexate

Euglycaemic ketoacidosis after fasting in a 58-year-old man with diabetes

Fever and rigors nine days after the first cycle of chemotherapy

Fever, facial swelling and rash after starting allopurinol in a 70-year-old man

Fever, rigidity and confusion in a 28-year-old man

Flushing, pruritus and hypotension during a rapid intravenous vancomycin infusion in a 45-year-old man

Fresh rectal bleeding and haemoglobin drop in a 70-year-old man on rivaroxaban and naproxen

Haematemesis in a 68-year-old on ibuprofen and low-dose aspirin

Hyperkalaemia and gynaecomastia in a 66-year-old man on ramipril and spironolactone

Hyponatraemia and unsteadiness in a 45-year-old man on carbamazepine

Increasing drowsiness and respiratory depression in an older patient with renal impairment

Jaundice and elevated ALT in a woman on tuberculosis treatment

Lip and tongue swelling in a 60-year-old man

Lithium toxicity after introduction of bendroflumethiazide

Maculopapular Rash in a 19-Year-Old on Antibiotics for Sore Throat

Melaena and INR 8.5 in a 76-year-old woman on warfarin after starting clarithromycin

Nausea, yellow-tinged vision and bradycardia in an 80-year-old woman on digoxin

New-onset agitation and grandiose ideas in a patient started on high-dose steroids

Painful sunburn-like rash after beach holiday in a young woman on acne treatment

Palpitations and a QTc of 520 ms in a 60-year-old woman

Paracetamol-induced hepatotoxicity in a patient with alcohol dependence

Peripheral oedema after six weeks of amlodipine

Profuse Diarrhoea and Fever in an 80-Year-Old After Antibiotic Therapy

Prolonged hypoglycaemia in an 84-year-old man with chronic kidney disease

Recurrent nocturnal hypoglycaemia after basal insulin increase and exercise programme

Restlessness, tremor and jaw stiffness in a 24-year-old woman given metoclopramide for vomiting in pregnancy

Rhabdomyolysis in a patient with suspected drug interaction

Severe Lactic Acidosis and Acute Kidney Injury in a 74-Year-Old Woman

Sore throat, fever and neutropenia in a patient on clozapine

Statin-induced myopathy after a dose increase in a 66-year-old woman

Vertigo and hearing loss in a patient with infective endocarditis

Weight loss, tremor, and atrial fibrillation recurrence in a 68-year-old man on an antiarrhythmic agent

Wheeze and reduced peak flow in a 55-year-old man with asthma after starting propranolol